Detalhe da pesquisa
1.
Barcoded Asaia bacteria enable mosquito in vivo screens and identify novel systemic insecticides and inhibitors of malaria transmission.
PLoS Biol
; 19(12): e3001426, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34928952
2.
Gametocytes from K13 Propeller Mutant Plasmodium falciparum Clinical Isolates Demonstrate Reduced Susceptibility to Dihydroartemisinin in the Male Gamete Exflagellation Inhibition Assay.
Antimicrob Agents Chemother
; 62(12)2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30224530
3.
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941635
4.
Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.
J Antimicrob Chemother
; 73(5): 1279-1290, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420756
5.
Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and Mefloquine.
Antimicrob Agents Chemother
; 60(5): 3145-7, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26902763
6.
A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents.
Malar J
; 15(1): 385, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27448565
7.
Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.
Antimicrob Agents Chemother
; 59(6): 3298-305, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801574
8.
Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.
Antimicrob Agents Chemother
; 57(7): 3268-74, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629698
9.
Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355750
10.
Red blood cells derived from peripheral blood and bone marrow CD34⺠human haematopoietic stem cells are permissive to Plasmodium parasites infection.
Mem Inst Oswaldo Cruz
; 108(6): 801-3, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24037205
11.
Cyclopropyl carboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screen.
Antimicrob Agents Chemother
; 55(12): 5740-5, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21968362
12.
Potent antimalarial 4-pyridones with improved physico-chemical properties.
Bioorg Med Chem Lett
; 21(18): 5214-8, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21824778
13.
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides.
Br J Pharmacol
; 178(2): 363-377, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085774
14.
The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957.
Sci Rep
; 11(1): 1888, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479319
15.
Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials.
J Med Chem
; 51(9): 2845-52, 2008 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18396855
16.
Effect of the haematocrit layer geometry on Plasmodium falciparum static thin-layer in vitro cultures.
Malar J
; 7: 203, 2008 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18842144
17.
A high throughput screen for next-generation leads targeting malaria parasite transmission.
Nat Commun
; 9(1): 3805, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228275
18.
Synthesis and Structure-Activity Relationships of the Novel Antimalarials 5-Pyridinyl-4(1 H)-Pyridones.
J Med Chem
; 61(8): 3422-3435, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29589932
19.
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Nat Commun
; 8: 15160, 2017 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28513586
20.
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nat Commun
; 8: 15159, 2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537265